Antibiotic Resistance Ontology Jamboree
IIDR scientific director Gerry Wright's research lab recently participated in a full-day meeting of the minds. The Antibiotic Resistance Ontology Jamboree was part of an ongoing development of a comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca). Ontologies provide a controlled vocabulary for organizing and classifying biological information. The Antibiotic Resistance Ontology forms the essential foundation for informatics tools such as CARD to annotate, classify and study resistance genes emerging from genomic studies. For example, searches of CARD based on the CTX-M ontology term will find all genes, protein structures, resistance mechanisms, publications, or other data associated with CTX-M ß-lactamases regardless of the quality of the original annotations or data source. This provides tremendous added value for a field such as antibiotic resistance that has multiple practitioners with diverse goals.
May 2, 2011